The Clinton Health Access Initiative, Inc. (CHAI) is a global health organization committed to our mission of saving lives and reducing the burden of disease in low-and middle-income countries. We work at the invitation of governments to support them and the private sector to create and sustain high-quality health systems.

CHAI was founded in 2002 in response to the HIV/AIDS epidemic, with the goal of dramatically reducing the price of life-saving drugs and increasing access to these medicines in the countries with the highest burden of the disease. Over the following two decades, CHAI has expanded its focus. Today, along with HIV, we work with our partners to prevent and treat infectious diseases such as COVID-19, malaria, tuberculosis, and hepatitis. Our work has also expanded into cancer, diabetes, hypertension, and other non-communicable diseases, and we work to accelerate the rollout of lifesaving vaccines, reduce maternal and child mortality, combat chronic malnutrition, and increase access to assistive technology. We are investing in horizontal approaches to strengthen health systems through programs in human resources for health, digital health, and health financing. With each new and innovative program, our strategy is grounded in maximizing sustainable impact at scale, ensuring that governments lead the solutions, that programs are designed to scale nationally, and learnings are shared globally.

At CHAI, our people are our greatest asset, and none of this work would be possible without their talent, time, dedication, and passion for our mission and values. We are a highly diverse team of enthusiastic individuals across 40 countries with a broad range of skill sets and life experiences. CHAI is deeply grounded in the countries we work in, with the majority of our staff based in program countries. Learn more about our exciting work: http://www.clintonhealthaccess.org

CHAI is an Equal Opportunity Employer, and is committed to providing an environment of fairness, and mutual respect where all applicants have access to equal employment opportunities. CHAI values diversity and inclusion, and recognizes that our mission is best advanced by the leadership and contributions of people with diverse experience, backgrounds, and culture.

Overview of CHAI’s Global TB Program

Tuberculosis is the world’s deadliest infectious disease. More than 10 million people fall ill each year, and 1.2 million die, with a disproportionate burden in sub-Saharan Africa and South and Southeast Asia. Roughly 40% of TB cases remain undiagnosed, fuelling ongoing transmission in communities. Children under five, people living with HIV, and those in underserved or displaced populations face the greatest risk.

CHAI partners with governments, multilateral organizations, and suppliers to close critical gaps across the TB care cascade. Our work spans three interconnected domains:

• Screening and diagnosis: accelerating the adoption of digital chest X-ray with AI, near-point-of-care molecular diagnostics, tongue swabs, and sample pooling strategies that bring accurate, rapid testing closer to patients.
• Treatment and prevention: expanding access to shorter, more effective regimens for both active and latent TB, with particular focus on community-based delivery of TB preventive therapy to children under five and other high-risk household contacts.
• Market shaping: negotiating price reductions, supporting generic product development, and ensuring sustainable supply of quality-assured TB commodities, from rifapentine-based preventive regimens to next-generation diagnostic platforms.

The program currently operates across 13 countries in Africa and Asia. CHAI’s Global TB Team provides strategic direction, technical leadership, and coordination across these country programs, while managing relationships with key funders and partners including the Global Fund, Gates Foundation, Unitaid, FCDO, GiveWell, Stop TB Partnership, and national TB programs.

Role Overview

This is a defining moment for TB. New diagnostic tools, shorter treatment regimens, and growing political will are converging to create a window of opportunity to dramatically reduce the toll of this disease. At the same time, uncertain funding landscapes, fragmented health systems, and the sheer scale of the undiagnosed burden demand a leader who can operate with both strategic ambition and operational discipline.

We are looking for a Senior Director who will serve as CHAI's most senior voice on TB, both internally and externally. This person will set a clear programmatic vision, articulate it compellingly, and bring a wide range of audiences along: country teams translating strategy into action, donors weighing where to invest, and government leaders deciding how to allocate scarce resources. The TB landscape involves a rich ecosystem of multilateral organizations, bilateral donors, research institutions, civil society, and national programs, each with distinct mandates, priorities, and ways of working. Success in this role requires someone who can build trust and find common ground across that ecosystem, forging alignment where interests converge and navigating constructively where they diverge.

TB kills more people than any other infectious disease, yet it is both preventable and curable. Breakthroughs in diagnostics, shorter and more tolerable treatment regimens, and the emergence of community-based delivery models have created real momentum. CHAI is at the center of that momentum, with the relationships, operational reach, and market shaping expertise to turn promising innovations into population-level impact. The Senior Director will have the platform and the organizational backing to lead one of the most consequential programs in global health today.

Reporting to the Vice President, HIV, Hepatitis & TB, the Senior Director will be responsible for shaping a portfolio that spans community-based prevention pilots, diagnostic technology introduction, market shaping interventions, and operational research across multiple countries. The ideal candidate brings deep TB expertise and a track record of delivering sustainable public health impact in low- and middle-income countries. They will set a compelling strategic direction that galvanizes teams and partners and translates into measurable, large-scale impact in the countries where TB takes its greatest toll.

Strategy and Program Leadership

• Define and communicate a bold strategic direction for CHAI's global TB portfolio, translating organizational priorities, donor expectations, and the evolving needs of high-burden countries into a coherent vision that the team, partners, and governments can rally behind.
• Scan the horizon for shifts in TB financing, epidemiology, policy, and the diagnostic and therapeutic pipeline; position CHAI to respond proactively and shape the conversation.
• Make disciplined strategic choices about where CHAI should focus, including decisions to scale, pivot, or wind down workstreams based on evidence, impact, and changing conditions.
• Develop multi-year programmatic plans, budgets, and performance management systems that drive accountability and continuous improvement across the portfolio.
• Champion the translation of evidence and operational learning into scalable, government-led program models. Orient the program at every stage toward government ownership, from design through financing and scale-up, so that impact endures beyond CHAI's engagement.

Resource Mobilization and Donor Management

• Lead development and execution of CHAI's TB resource mobilization strategy, ensuring the program has the funding to match its ambition and building resilience against shifts in the global aid landscape.
• Identify and pursue non-traditional funding opportunities, making the case for TB investment to new donors and positioning CHAI's TB work within broader global health and development agendas, including the growing interest in AI-enabled health solutions.
• Manage major donor relationships and program finances, ensuring high-quality reporting, proactive risk management, and disciplined deployment of resources.

Technical Leadership

• Set the intellectual agenda for CHAI's TB work: define the questions the organization should be asking, identify where conventional approaches are falling short, and push the team to develop stronger answers.
• Provide hands-on technical guidance to country and regional teams on complex programmatic, policy, and scientific questions spanning diagnostics, treatment, prevention, and service delivery.
• Drive CHAI's TB learning and research agenda, including operational research, impact evaluations, cost-effectiveness analyses, and data-driven refinements to program design, ensuring that findings are translated into action.
• Stay ahead of the frontier of TB science and innovation, ensuring CHAI is positioned to move quickly as new screening, diagnostic, and treatment tools emerge.

External Representation and Ecosystem Influence

• Represent CHAI at the highest levels of the global TB community, from ministerial meetings to donor convenings to technical forums.
• Actively shape how the global community prioritizes, funds, and organizes the TB response, bringing evidence and operational insight to bear on policy and investment decisions.
• Strengthen CHAI's positioning as a trusted partner and thought leader in the TB ecosystem, known for evidence-informed approaches and a commitment to practical, scalable solutions.
• Build and sustain trusted relationships across a diverse ecosystem of multilateral organizations (WHO, the Global Fund, Stop TB Partnership), bilateral donors, academic institutions, suppliers, implementing partners, and civil society, understanding each partner's priorities and finding productive ways to collaborate toward shared objectives.
• Navigate a multi-stakeholder landscape with diplomacy and strategic clarity, identifying opportunities for collective action while ensuring CHAI's distinctive contributions are well understood and valued.
• Contribute to shaping the global policy environment for TB, including regulatory pathways, normative guidance, and investment frameworks.

Team Leadership and People Development

• Lead, develop, and grow a diverse, high-performing team, strengthening the team's capabilities over time to keep pace with the program's evolving ambitions
• Provide direct management and mentorship to senior team members, including coaching managers of people, investing in their professional development and enabling them to lead their respective portfolios with confidence and autonomy.
• Foster a team culture grounded in intellectual rigour, collaboration, accountability, and continuous learning.

Organizational Leadership and Cross-Cutting Collaboration

• Own the TB program's results. Be accountable not only for how the work is managed but for what it achieves: reductions in undiagnosed TB, expanded preventive treatment coverage, and sustainable improvements in how countries detect, treat, and prevent the disease.
• Work in close partnership with CHAI country directors and country-based staff, recognizing that the strongest global strategies are built on the insights, relationships, and operational realities that country teams bring
• Collaborate closely with leaders across CHAI's HIV, Diagnostics, Markets, Health Systems, and AI programs to identify synergies, share learning, and pursue integrated approaches where they strengthen impact.
• Contribute to organization-wide initiatives that strengthen CHAI's culture, effectiveness, and ability to adapt to a rapidly changing global health landscape.

• 12+ years of progressive experience in a related field, with increasing levels of responsibility and leadership.
• Strong working knowledge of the global TB landscape, including familiarity with TB epidemiology, diagnostics, therapeutics, and the key donor and policy environment.
• Demonstrated success leading global or multi-country programs, with a clear track record of achieving measurable public health impact in low- and middle-income countries.
• Outstanding communicator who can distill complex technical and strategic issues into clear, persuasive narratives for varied audiences, and who uses communication deliberately to build consensus, inspire action, and sustain momentum behind a shared vision.
• Strong resource mobilization experience, including leading successful proposal development and donor engagement for large, multi-year grants.
• Excellent project and people management skills, including designing and managing cross-functional teams spanning multiple geographies and time zones.
• Demonstrated high bar for quality, analytical rigor, and attention to detail in programmatic outputs and strategic deliverables.
• Track record of building and managing relationships with senior government officials, multilateral organizations, and major institutional donors, with demonstrated ability to align diverse stakeholders around a common agenda and maintain productive partnerships even when organizational interests do not fully overlap.
• Entrepreneurial mindset, with the ability to identify and pursue new opportunities, work independently, and drive initiatives forward in fast-paced, limited-structure environments.
• Ability and willingness to travel internationally, 25-30% of the time.

Advantages:

• Deep expertise in tuberculosis, including thorough knowledge of the global TB policy and financing architecture, health systems delivery, or TB clinical management.
• Prior experience working with or within national TB programs, the Stop TB Partnership, the Global Fund, Gates, or Unitaid.
• Experience in market shaping, health commodity procurement, or access-to-medicines initiatives in a global health context.
• Experience living and working in sub-Saharan Africa, South or Southeast Asia, or other high-TB-burden regions.
• Advanced degree in management, public health, science, or other relevant fields a plus.

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