The Clinton Health Access Initiative, Inc. (CHAI) is a global health organization committed to saving lives and reducing the burden of disease in low-and middle-income countries, while strengthening the capabilities of governments and the private sector in those countries to create and sustain high-quality health systems that can succeed without our assistance. For more information, please visit: http://www.clintonhealthaccess.org
Overview of Team:
The Process Chemistry Team (PCT) was founded early in CHAI’s mission to add technical credibility to price negotiations with generic partners and to focus negotiation efforts on rational antiretroviral (ARV) drug targets. This expertise has allowed CHAI to direct purchasing programs toward suppliers who can deliver quality drugs at the best prices. After learning how lower manufacturing costs could improve their profitability and market share, drug manufacturers may be encouraged to implement these technical innovations. To this end, PCT began networking with collaborators to develop research contracts with various groups and establish a chemistry laboratory to conduct background analyses of manufacturing processes, and perform and coordinate process chemistry research to optimize active pharmaceutical ingredients (API) manufacturing in the areas of HIV, malaria, direct-acting antivirals for hepatitis C, tuberculosis, and several essential medicines. Recently, PCT has expanded its scope to work on new drug products for low/middle income countries (LMICs) in early development.
Overview of Role:
This Scientific Director will work closely with the Director of Process Chemistry, other Process Chemistry team members, and CHAI partners to support the development of long-acting formulations of drugs. The work will include optimizing and scaling up APIs in the CHAI laboratory and supporting good manufacturing processes (GMP) of clinical trial material. This individual will have overall responsibility for designing and implementing experiments in the CHAI lab and ensuring high quality data is collected, analyzed, communicated and stored appropriately.
This role is based in Newark, Delaware, United States.